In the pharmaceutical formulation Malegra, two active substances are combined: Sildenafil This drug's dual action makes it very special since each ingredient has a specific function in treating various illnesses. First off, sildenafil is a powerful vasodilator that is a member of the phosphodiesterase type 5 (PDE5) inhibitor medication family. Its main function is to treat erectile dysfunction (ED), a disorder in which men have trouble getting or keeping an erection strong enough for intercourse. When sexually excited, cyclic guanosine monophosphate (cGMP), which encourages smooth muscle relaxation in the penis and increases blood flow, can be broken down by the enzyme PDE5, which sildenafil inhibits. This makes it easier to achieve an erection.